In-silico Drug
Discovery: We are addressing this space
through a parallel drug discovery software
suite, along with underlying HPC.
Motif Discovery
A fraction of the
genome across species is conserved over
millions of years. Identifying these
conserved regions (motifs) is
computationally challenging. We are
developing a parallel motif discovery
software suite with application to gene
regulation, evolutionary biology and DNA
looping.
Sequence Alignment
Data base search is the
key to successful bioinformatics. We have
parallelized existing standalone
implementations of:
i. Basic Local
Alignment Search Tool (BLAST) from NCBI
ii. Smith Waterman from
FASTA
Neurosimulation
We have parallelized an
existing standalone neurosimulator called
MOOSE. Our contribution is available as a
Beta release on the MOOSE site (http://moose.sourceforge.net).
